![Andrew Steele](/img/default-banner.jpg)
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Andrew Steele
Germany
Приєднався 19 січ 2012
Physicist-turned-biologist talking aging, AI and more. I wrote a book called Ageless. Check it out at ageless.link!
The world’s largest prize: interview with @peterdiamandis and Jamie Justice
Want a chance to win part of a $101 million prize pot? All you need to do is restore an older person’s function by 10+ years and you could be in with a chance of winning the new XPRIZE Healthspan! I spoke to two of the project leads, Peter H. Diamandis and Jamie Justice, to find out whether we really can move the needle on this, why they made this a prize rather than just handing $101 million to longevity scientists, why more billionaires aren’t doing this, and, most importantly…why one hundred and one million dollars?
Thanks to Peter and Jamie, and @xprize for making this video possible!
You can find out more about XPRIZE Healthspan at www.xprize.org/prizes/healthspan
And you can check out the free chapter of my book on the ethics of aging biology at ageless.link/ethics
Chapters
00:00 Introduction
01:24 Why $101 million?
02:20 What do you need to do to win?
05:27 What kinds of interventions are you expecting?
09:00 What’s the baseline?
11:26 Where did the money come from?
13:28 Why aren’t billionaires more interested in aging?
17:14 Challenging ethical questions
24:26 Why do this as a prize?
28:20 Questions from social media
32:48 Conclusion
Credits
Cash register sound CC-BY user Benboncan on Freesound freesound.org/people/Benboncan/sounds/91924/
And finally…
Follow me on Twitter statto
Follow me on Instagram andrewjsteele
Like my page on Facebook DrAndrewSteele
Follow me on Mastodon mas.to/@statto
Read my book, Ageless: The new science of getting older without getting old ageless.link/
Thanks to Peter and Jamie, and @xprize for making this video possible!
You can find out more about XPRIZE Healthspan at www.xprize.org/prizes/healthspan
And you can check out the free chapter of my book on the ethics of aging biology at ageless.link/ethics
Chapters
00:00 Introduction
01:24 Why $101 million?
02:20 What do you need to do to win?
05:27 What kinds of interventions are you expecting?
09:00 What’s the baseline?
11:26 Where did the money come from?
13:28 Why aren’t billionaires more interested in aging?
17:14 Challenging ethical questions
24:26 Why do this as a prize?
28:20 Questions from social media
32:48 Conclusion
Credits
Cash register sound CC-BY user Benboncan on Freesound freesound.org/people/Benboncan/sounds/91924/
And finally…
Follow me on Twitter statto
Follow me on Instagram andrewjsteele
Like my page on Facebook DrAndrewSteele
Follow me on Mastodon mas.to/@statto
Read my book, Ageless: The new science of getting older without getting old ageless.link/
Переглядів: 2 761
Відео
Welcome to the Andrew Steele YouTubeCast
Переглядів 7825 місяців тому
Welcome to the Andrew Steele UA-camCast! This is a quick introductory video for a playlist of videos that you might want to listen to rather than watch, like interviews. I can’t promise I’ll add to it regularly, but I thought it was worth trying out in case it’s useful for anyone! Enjoy. :) Follow me on Twitter statto Follow me on Instagram andrewjsteele Like my page o...
Why I disagree with @PeterAttiaMD
Переглядів 14 тис.6 місяців тому
Could @PeterAttiaMD live to 150? He recently told his podcast audience he’s bored of ‘sci-fi’ portrayals of ageing biology-and so am I!-but here’s why I think Peter living to 150 years old is not sci-fi…it just requires far greater investment in longevity research. To be clear, I still think it’s far from certain that Peter will hit the big 120-but I think he’s missing something important when ...
Blood pressure and heart rate variability explained
Переглядів 41 тис.9 місяців тому
For more on wearables, including two more videos with the amazing @MedlifeCrisis, go here: ua-cam.com/play/PLg0VbZ0kyCHl0yKBAQZ0NaI-Gxax6_0oX.html You’ve probably heard that blood pressure is important-but what is a healthy blood pressure, how can you check yours, what can you do to improve it, can it be measured from a smartwatch, and…which is higher, a deadlifter’s blood pressure, or a giraff...
The most exciting REAL anti-aging drugs
Переглядів 63 тис.10 місяців тому
Find out more about real anti-aging drugs in my book, _Ageless: The new science of getting older without getting old_ ageless.link/ Or watch more longevity videos in my playlist: ua-cam.com/play/PLg0VbZ0kyCHmO8iGdXdg_FudrWauf48BT.html *Chapters* 00:00 Introduction 00:46 Rapamycin 02:34 Senolytics 04:49 Metformin 06:18 Taurine 07:24 Statins 09:54 Conclusion *Sources and further reading* If you w...
10 amazing things you CAN’T do with ChatGPT
Переглядів 19 тис.10 місяців тому
Could ChatGPT…destroy the world? Watch this to find out: ua-cam.com/video/3CRZjrndFoU/v-deo.html There are _so many_ videos online about using AI for research, to summarise complex ideas or to write your emails for you. But what they don’t tell you is that ChatGPT, and other ‘large language models’ like Google Bard and Microsoft Bing lie, make stuff up, give out dangerous information (all you h...
How Oppenheimer could REALLY have destroyed the world
Переглядів 3,8 тис.11 місяців тому
How Oppenheimer could REALLY have destroyed the world
How AI could destroy the world by accident
Переглядів 6 тис.Рік тому
How AI could destroy the world by accident
How tiny bubbles of fat could revolutionize medicine
Переглядів 4,4 тис.Рік тому
How tiny bubbles of fat could revolutionize medicine
The EXTREME science of making microchips
Переглядів 6 тис.Рік тому
The EXTREME science of making microchips
The most important number for your health (feat. @MedlifeCrisis)
Переглядів 139 тис.Рік тому
The most important number for your health (feat. @MedlifeCrisis)
How gene editing could save Chris Hemsworth
Переглядів 13 тис.Рік тому
How gene editing could save Chris Hemsworth
Can ‘Blueprint’ make you biologically younger?
Переглядів 140 тис.Рік тому
Can ‘Blueprint’ make you biologically younger?
The best Wordle strategy - according to science
Переглядів 891 тис.2 роки тому
The best Wordle strategy - according to science
Coronavirus: how bad is the new Omicron variant?
Переглядів 6 тис.2 роки тому
Coronavirus: how bad is the new Omicron variant?
Would curing aging destroy the planet?
Переглядів 8 тис.2 роки тому
Would curing aging destroy the planet?
Ageless: How to slow your own ageing
Переглядів 6 тис.3 роки тому
Ageless: How to slow your own ageing
Ageless: The new science of getting older without getting old
Переглядів 3,4 тис.3 роки тому
Ageless: The new science of getting older without getting old
How science can reverse aging - and why we’d want to
Переглядів 17 тис.3 роки тому
How science can reverse aging - and why we’d want to
Coronavirus vaccine: how excited should we be?
Переглядів 2,4 тис.3 роки тому
Coronavirus vaccine: how excited should we be?
How we could do TEN TIMES more covid tests, for free
Переглядів 33 тис.3 роки тому
How we could do TEN TIMES more covid tests, for free
Mars won’t be this bright again until 2̶0̶3̶5̶ 2033
Переглядів 46 тис.3 роки тому
Mars won’t be this bright again until 2̶0̶3̶5̶ 2033
Risk of death increases with age.
I am using W3W to tell people the location of trees. Readings on my phone tell me the GPS inaccuracy. This can be 10s of meters. If the tree is in a street I use the initial reading to go to the web site and use the street view to more accurately pinpoint the centre of the tree. If the tree is in a wood I can't pick out a particular tree from the large green area so the W3W is less useful, but it is still useful. Obviously any system will be limited by GPS accuaracy.
This Steele guy reminds me of the political libertarian guy Steele who also explores random topics in interview form
An interesting connection to taurine is that the blue zones studies found every group to eat a high amount of beans. Beans are high in taurine. Although seaweed is higher and easier to supplement with. Unfortunately the studies author keeps saying it’s just a plant based diet which doesn’t track otherwise vegetarians would have a solid track record of long life.
,🇵🇬🇵🇬
🇵🇬,.,.
What about putting lime in Corona beer ?
Just worry about working on your cardio. You can easily take your heartrate yourself. I have a Garmin dive watch and its very inaccurate. Tattoos, sweat, hair and placement all contribute.
54 years old , Resting heart rate mine 49 ,correlated VO2 , good to know this , my cac score is 600 , even I think I have a strong heart rate. I should lower my statin mg
Yes
Why are his eye brows smiling so much lol
What about taking your watch off before bed?
Fully tested with my wordle ai (crane)
Excellent demonstration, loved the overall quality of the content. Enjoyed very much
we have a post code so don't need this three word thingy
Sleeping is quite literally resting...
Another complication to consider is software updates, if you try to monitor your RHR over time is the change you observe merely due to modified algorithms. 🤔
Moustache is very distracting from the good information he's sharing. Also could the guys have any smaller, shittier chairs? 🤔
Don’t knock the chairs, they were very comfy
You can trust in almost everything because modern smart watches are accurate but only except blood pressure. It's useless and of course not accurate and you completely should ignore it.
All I can say is that my Apple Watch has potentially saved my life- twice. It’s informed me about severe AF that I suffer from, twice. As for steps: my wife has a Fitbit, (which she hates) and when we walk the distance and steps are incredibly accurate between my Apple Watch and her FitBit. She’s had three fitbits, first two failed during warranty- absolutely appalling reliability. She now wants an Apple Watch, only disadvantage being reduced battery life. When her FitBit inevitably dies again, that’s what we will get.
My smartwatch told me my RHR was as low at 36BPM. luckily, it was correct and warned me appropriately after the doctor did a 24 HR ECG and found a heart issue.
Mine seems reasonably accurate. Had a hernia Op 7 weeks ago. They hooked me up to all the machines and suddenly alarms started going off. My heart rate was showing 43, about right for what my watch shows. Although it leapt to almost 50 when all the alarms started going off, until they explained why. Once I told them I was an ultra runner they were fine.
The Federal government has no incentive to increase fund research into extending life span. The treatments sound too expensive for an already over-extended Medicare and even now life spans may be too long be able to support Social Security for the existing, increasing elderly population. There may not be an active conspiracy around this, but it's certainly in the backs of some policy maker's minds.
We should tell them the good news: these treatments will probably save money! Slowing aging would delay diseases like cancer and dementia which are hugely expensive to treat, and have large wider economic costs too. I suspect you’re right that it’s ignorance rather than conspiracy, which hopefully means we’ve got the opportunity to change a few minds! :)
it's misleading to say the oura ring is lying in this context. it's marketed a sleep wearable.
Hats off to the skeleton with a pelvis instead of a skull.
I only wear my watch during the day and the resting heart rate is still in the 40s, according to the Garmin watch.
You can check your resting heart rate during the day by stopping for a bit and checking. You can’t check your watch during the night, or during your absolute resting heart rate, so that’s why you should get that reading.
wait lmao you people wear these when you sleep too jfc get therapy
Statins 👎👎👎👎👎
Do the thumbs indicate the direction of LDL cholesterol levels?
@@DrAndrewSteele the thumbs down indicate my attitude to statins. There is enough evidence RCT's + epidemiological to question the efficacy of statins. Plus there is the level of injury. I suffered muscle weakness balance problems for years before my suggested dropping statins. I have not taken them again. The Japanese study measures ACM vs cholesterol level. Lower cholesterol = higher mortality.
Lmao I RAAANNN to the comments
Wearables are never going to be as good as a proper GE/Dynascope/etc machine you'll find in a hospital but for making you aware that your HR is high, your ECG is off etc and you need to seek medical help they've proven to be quite useful in that regard
🇵🇬🇵🇬.,,.
*breathes in audibly*
Nice to know. Oldie days measured by feel. 15 seconds try a few times see if consistent count. Not convenient but can reasonableness check HRM. Chest straps tend to be more accurate.
Me with my apple watch RHR reading of 92: 🥲💀
Someone didn’t turn on his sleep focus mode on the Apple Watch. If you do that, the Apple Watch won’t take into account the sleeping heart rate for the calculation of the resting heart rate.
This video has just gone mildly viral a couple of years after I actually did the tests… I think software updates have fixed this for Apple now (though the fact that on such an expensive and accurate watch you have to manually enable sleep tracking and specify the time blows my mind a bit! Not an Apple Watch owner, have I understood that correctly? I need to borrow one again or buy my own to run a few more tests. :) )
My Apple Watch is reporting a resting heart rate that is actually pretty close to what it is measuring during the day, while I am sitting at my desk, though it doesn't actually differ significantly from my sleeping heart rate (maybe 5bpm difference)
My apple watch was warning me about low heart rate while I'm asleep. I was pretty concerned and consult with my doctor, did some measurements, wore a cardiologist device measuring me for 3 days while logging everything what happens to me. Everything was fine. Later it showed around 40 beats during the day, while I was actively talking and obviously didn't have that low numbers. I'm happy for people who got important warning in time, but for me it gave only anxiety 😢
This is the complete wrong way to look at any of this data. These sensors are all pretty basic, on every watch. So are they inaccurate? Yes. But you made an entire video on it, which tells me you and others _miss the entire point_ The point is looking at the _trends_ over time. Did my RHR go down? Up? Did changes I make to my lifestyle like more sleep or exercise change my RHR? That's how you're supposed to measure and use the data. You'll need much better equipment for an accurate reading. But that ISNT necessary for trending data. All you need is a starting point and then data over time to look at changes _over time_ . If it's off by 5 or 10% doesn't matter for 90% of the analytics we would need from one of these watches.
Take phone, Place over heart, record audio for 20sec, trim video to 20sec exact, count beats, multiply by 3, bpm calculated, mine was 57
Imagine just having a normal conversation while sporting that mustache, as though you're just a real person.
Lmao mine is a resting of 78 💀
I think your watches are broken. I had a few (Sony,noname,Xiaomi) , and they all indicated my correct RHR (range between 90-105) . This was also confirmed by a scale.
The whole video looks weirdly sped up. Looks so unnatural. Maybe practice delivering the lines faster so you don’t have to speed up the video as much.
I wear oura and my resting heartrate is 68....am I gonna die? 😂
My FitBit and Apple Watch returned similar resting heart rate measurements. A fun observation of my own health is that my resting heart rate is higher when I’m sleep deprived.
Just like a power meter on a bicycle. Your data is only comparable to your own equipment no on else's. You can see overall trends. If you have a same device for 3-5 years it far more useful to look at trends you and device has. These companies have a disclaimer, these are not medical devices. If you suspect you have a health issue you seek out a doctor.
There are some studies in males showing that a lot of the age associated loss of VO2 Max is not wholly inevitable and can be mitagated by serious exercise. I'm a little uncomfortable about how you discussed that part but I enjoyed the video.
People want to obsess over these things but dividing things up by quartiles or quintiles, of any of these metrics, is about the highest level of exactitude you can really expect or put some stock in. I've read that resting heart rate can be genetically low or high but a change toward lower can be an indicator of fitness. Drastic changes should be run by a doctor though as it can go down or up for non-fitness related reasons. Comparisons between individuals may not work even though people want to do that so bad! It may be an internally consistent metric though. So many want it to be an externally consistent metric. It isn't at this level of testing/measuring. This is a lot like bodyfat testing. You might actually have a 3% drop but you might not really know your actual bodyfat percentage with the same accuracy as your estimation of drop. It's still useful to compare yourself to yourself but less good to compare yourself to others which is what so many want. I'm suggesting that might be something to deemphasize and for more than one reason.
If my RHR was 35-48 even while awake I'd probably think "hey, that's neat" while also making a doctor's appointment